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« Did The Left "Celebrate" The Death of the 2000th Hero? | Main | Making National Security Fun »
October 28, 2005

Descendants Of Bubonic Plague Survivors Resistant To AIDS?

I think this may be kinda old, but very cool nonetheless.

Local Eyam lore tells befuddling stories of plague survivors who had close contact with the [bubonic plague] bacterium but never caught the disease. Elizabeth Hancock buried six children and her husband in a week, but never became ill. The village gravedigger handled hundreds of plague-ravaged corpses, but survived as well. Could these people have somehow been immune to the Black Death?

Stephen O'Brien of the National Institutes of Health in Washington D.C. suggests they were. His work with HIV and the mutated form of the gene CCR5, called "delta 32," led him to Eyam. In 1996, research showed that delta 32 prevents HIV from entering human cells and infecting the body. O'Brien thought this principle could be applied to the plague bacteria, which affects the body in a similar manner.

Thanks to Kevin.


posted by Ace at 08:34 PM
Comments



Not sucking the pustules of the inflicted is key to not getting infected.

Posted by: on October 28, 2005 08:37 PM

There was an episode of "Secrets of the Dead" devoted to this not long ago. Absolutely worth Tivoing the rerun. Best show on TV.

Posted by: Allah on October 28, 2005 08:48 PM

I'd always wondered if my parents were bullshitting me when they said that our family's robust health was due to the fact that our ancestors gang-fucked plague-bearing rats. Guess not.

Posted by: Andrew on October 28, 2005 09:13 PM

And to think of all that time - all those lives - wasted on gerbils. So close... so close.

Posted by: VRWC Agent on October 28, 2005 10:18 PM

Ace -

If you search your memory, you'll realize this was an early 80s TV movie, the exact name of which I forget.

Basically, a plague swept the world. If you had a certain genetic characteristic, you were fine. If not, you turned into some sort of powdery thing.

The plot hinged on a parent finding themselves to be immune but the rest of the family was not.

Television - is there anything it cannot prepare us for?

Posted by: BumperStickerist on October 28, 2005 10:30 PM

Television - is there anything it cannot prepare us for?

Yeah, infomercials.

Posted by: on October 28, 2005 10:38 PM

I think you may be talking about "Where have all the people gone?"

This report seems vaguely implausible to me, in as much as the infection mechanism used by HIV (or any virus) is really pretty much totally unlike the mechanism used by Bubonic Plague (or any bacterial disease). They don't have anything to do with one another except for the fact that they both like chowing down on humans.

Posted by: Steven Den Beste on October 28, 2005 11:09 PM

I seem to remember reading that we don't actually know for sure that the Black Death was bubonic plague. I think there is considerable speculation that it was possibly a viral disease along the lines of Ebola. If so, this genetic immunity would make more sense.

Just my $.02,
DRK

Posted by: DaveK on October 29, 2005 02:45 AM

I remember that TV movie. I quite liked it and was disappointed it didn't go to series, but then I was ten years old at the time. The later classic 'Night of the Comet' seems to have drawn some inspiration from that source.

"Lets play a game! It's called Scaaary Noises!"

http://www.amazon.com/gp/product/0425196461/103-5387391-2265400?v=glance&n=283155&s=books&v=glance

I recently tried to read a novel based on a similar premise in which small pox exposure caused a gene to become active that conferred AIDS resistance. It is pretty obvious the author had read Richard Preston's excellent 'Demon in the Freezer' and some other material to inspire this dreck. The plot required so many ridiculously improbable events and behaviors it became impossible to continue after the first third. Other than the ideaof creating a medical thriller on the premise of a beneficial use of small pox, there wasn't a single original idea in the waste of paper.

Posted by: epobirs on October 29, 2005 07:08 AM

I'll tell you what went wrong with the plague - too many rats, not enough cats!

Posted by: The 2000 Year Old Man on October 29, 2005 09:19 AM

Um, considering that a lot of us here are of European ancestry, isn't it safe to say that all of us are descendants of Black Plague survivors?

Posted by: V the K on October 30, 2005 05:49 PM

They say that the great french prophet NOSTODAMUS was a doctor who treated victims of the pleague with what were called ROSE LOSIGEZE

Posted by: SPURWING PLOVER on October 30, 2005 11:00 PM

Good job

Posted by: gang fucked on November 14, 2005 10:47 AM
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