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July 11, 2004
Sometimes Government WorksRare, but it does happen. The next time I don't notice how few Thalidomide-deformed Americans I'm not meeting, I'll try to remember that it was actually one good bureaucrat doing her job right I have to thank for that: As autumn closed in on the Christmas holiday season—the most lucrative time of the year for the sale of sedatives—the pharmaceutical company, frustrated by the repeated—and in their view, unnecessary—delays, began to pressure Dr. Kelsey with visits and phone calls to her superiors. Despite the increasing pressure, Dr. Kelsey remained steadfast in her demand for thorough clinical studies demonstrating the drug’s safety. ... In the few years that the drug was on the world market, thousands of children were born with Thalidomide-related deformities[6]. Many did not survive their first year. Countless more miscarriages were traced to the use of Thalidomide. The damage in the United States, due to the work of Dr. Kelsey, was small by comparison, with 17 children documented to have Thalidomide-associated deformities. These children were affected during clinical trials of the drug, prior to its approval. During this investigational period, Richardson-Merrell distributed more than 2.5 million Thalidomide tablets to more than 1,000 doctors who, in turn, gave the tablets to nearly 20,000 patients—several hundred of whom were pregnant women. posted by Ace at 12:04 AM
CommentsYeah, the problem is that there are people who are still trying to keep it off the market for people it can help. My mom has a terminal illness called scleroderma. Thalidomide has shown promise in treating this disease, as well as others. My mom, at 67, is well past menopause. Still, these activists will not allow the drug to be approved byt the FDA for *any* use. The weeping, hand-wringing busybodies go on "Oprah" and weep and wail about how "one baby is one two many", and the mindless audience weeps and applauds.... Posted by: Barry on July 11, 2004 12:10 AM
Interesting point. I hadn't realized anyone was still working with the drug for any purpose. Posted by: ace on July 11, 2004 12:18 AM
I wonder what other drugs were released prematurely under industry pressure? Probably a lot of them, but they didn't cause a problem. Posted by: lauraw on July 11, 2004 12:36 AM
The people I saw in Germany were my own age. It could have been me. It could have a lot of kids in my grade. All over America. My purpose was to praise one lady who resisted pressure to sign off on a morning-sickness drug that she was suspicious of. Posted by: Donnah on July 11, 2004 01:12 AM
My dad is a retired doctor, but he told me that the Thalidomide situation at the FDA was merely dumb luck many years ago. It was a lowly bureaucrat doing what they do naturally--mucking things up. I did a little Googling, and it does appear, as other commentators have brought up, that the drug is actually useful. Most drugs have side effects (most not quite as repugnant), but that is merely the nature of the business. Many drugs are poisons which are directed at cells which are killing or seriously harming people. Apparently this drug is no longer banned in the US. Apparently from at least a couple articles which I found at Google, my dad is not the only one to know that this FDA triumph is not as it has been portrayed by the bureaucratic types for many years. I live in one of the most liberal and nutty places in the USA (Multnomah County, OR). Even though many people gave convincing testimony that the arguments against foam drink and food containers were, at least now, not true, our trusty Portland City Council renewed their ban, simply on nostalgic reasons based on their old victories. Facts and reason are usually lost on bureaucrats, at least that has been my experience with liberal bureaucrats (I suppose that a few conservative bureaucrats do exist, but I have never met one). I do understand that this is a trivial example relative to the stakes involving any powerful drug, but I do think that it is telling. Posted by: Mike on July 11, 2004 08:08 PM
The lowly bureaucrat was also a doctor. The doctors at the CDC are bureaucrats. I'm a bureaucrat. Posted by: Donnah on July 11, 2004 09:20 PM
I'm with Barry on this one. Thalidomide can be used to help keep multiple myeloma, a type of cancer, in check. I'm sure it has other uses, as well. It's clear it should not be given to pregnant women, and there can be some unpleasant side effects, but that doesn't mean it should be banned entirely. If the choice is losing some sensation in ones extremeties (eg, fingers) and dying of cancer, I think I'd go along with the Thalidomide. If properly prescribed, it can be genuinely helpful. The word "properly" is key here, of course... Posted by: Tom on July 12, 2004 11:02 AM
"Properly" IS key. Bureaucrats have legal depts. that are out to nix anything that remotely smells of a lawsuit. Once the drug is approved the cat is out of the bag and a few "accidental" uses could make big trouble. You'll need some heavy lobbying to get Thalidomide approved. Posted by: dano on July 12, 2004 05:02 PM
crestor lawsuit Posted by: crestor lawsuit on April 25, 2005 06:08 PM
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Forgotten 80s Mystery Click
She's totally committed to major independence She's a lady through and through She gives them quite a battle, all that they can handle She'll bruise some, she'll hurt some too
Update to the video of a Russian soldier being spun around and thrown by the machinegun he was operating: The soldier was testing an old, archaic Russian machinegun intended to be mounted to a helicopter. The old gun was pressed into service as a possible anti-drone gun. The Russian army is generally depleted and being forced to bring a lot of old, unreliable weapons and platforms to the front.
Also: Ukranian drones have
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FDA is providing an update regarding the sample of lettuce supplied by Taylor Farms de Mexico which was reported positive on July 18, 2026. Due to the complexity in detection of Cyclospora, FDA laboratory experts re-reviewed the sample results and have concluded that the finding does not represent true amplification and should be considered a false positive. Information about the sample has been removed from the July 18, 2026, update below. FDA has notified Taylor Farms and continues working with the firm to ensure product implicated in this outbreak has been removed from the market. FDA and state partners continue to collect and analyze product samples. As of July 19, 2026, there are no confirmed positive sample results for product testing for Cyclospora.[CBD]
FEDERAL APPEALS COURT STRIKES DOWN
NJ "ASSAULT WEAPONS" BAN/MAGAZINE BAN! Let's see if it reverts to the previous 15 round limit or I can actually run my weapons as God intended! [CBD]
Forgotten 80s Mystery Click: Northern Lights Division
Our topic today is music That's right, like 'Cause my brother and I are now experts in the field, eh Yeah, right, 'cause we're a band now Uh, yeah, so Except for him, I'm a band Aw, how can you do that? You're making me look bad You're such a Hosehead
CNBC ranks Tennessee as dead last in its “Worst States to Live” analysis. The specific reason is that cross-dressing men in TN are denied access to children and women’s private spaces. Texas finished 49th. The “worst” states were all red states. [Buck]
Senator Lindsey Graham (R - SC) has died after a "brief and sudden illness." [Buck]
The "Evel Knievel Experience," a museum dedicated to the famous daredevil, opens in (where else) Las Vegas
Well I guess they could have opened it on the Snake Canyon.
In response to someone asking why the video tape doesn't show Tyler Robinson's face (PS, it does, but it's crappy video so it's blurry):
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