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November 17, 2017

Oh My: Anti-Aging Drug Trials To Begin in Dogs in 2019, and Humans In 2022, if the Dog Trials Are Successful?

What I'd give to be 29 again.

Why start with dogs? Interestingly, it's not just that dogs are a big animals with some similarities to humans. It's that if it works on dogs, bang, you have a salable product right there-- people will pay to de-age their beloved mutts.

Which would then fund the next research phase, for humans.

George Church describes the roadmap for to human aging reversal treatments

We will see the first aging reversal test in dog trials in the next year or two. If that works, human trials are another two years away, and eight years before theyíre done. Once you get a few going and succeeding itís a positive feedback loop.

His company Rejuvenate Bio is actually working on the dog trial now.

The particular dog model weíre using has a heart disease issue. Rejuvenate Bio is still semi-stealth mode, incubator mode, but the trial is not a secret. Dogs are a market in and of themselves. Itís not just a big organism close to humans. Itís something people will pay for. And the FDA process is much faster for dogs than for humans ó a little over a year versus nine years or so. Weíll do dog trials and thatíll be a product, and thatíll pay for scaling up in human trials.

FDA does not need to classify aging as a disease in order for them to treat it

The FDA does not need to classify aging as a disease. If you actually have something that causes aging reversal, [the FDA] will approve it. Youíll frame it in conventional terms, but it can have additional benefits. In other words If you have something that fixes one disease problem and happens to fix a bunch of others, you donít need to put them all on the label. The FDA doesnít stop you for using things off label or curing two things at once.

I mean, what I'd give to be 29 at some point this year. I'll be 29 then at some future date.

But what I'd give to then stay 29.

Bullshit? Probably. But... if the rule is "disbelieve 99% of what you read," fine, this is in the 1% I'm choosing to believe.


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posted by Ace at 08:00 PM

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