... over the longer term a sharp drop in levels of immune-suppressing IL-10, as well as PD-L1, both inducers of T-cell exhaustion, was associated with restoration of antiviral immune response and virus clearance. And although blocking the IFN-I-a-b receptor led to higher bloodstream levels of virus in the first days after infection, it soon brought about a stronger, infection-clearing response...
(4)SRI again -- this time they've discovered a way to treat prion diseases. Interestingly, one of the effective drugs uncovered was an OTC antihistamine withdrawn from the US market some years ago for causing rare cardiac arrhythmia, although its still commonly available overseas. Would you rather get dementia and die from mad cow or have a chirpy heart? I'd say there's no contest. This prion shit has been pretty scary in that there was no known treatments. Now there some hope.
Let's hope the new age of discovery isn't cut short... ...by the new dark ages