GAINZZZ and BRAINZZZ

Nina Teicholz, author of The Big Fat Surprise, publicizes a study. The experiment wanted to determine which of three diets -- low-carb (keto), low-fat, or vegan -- would produce the least weight gain on an overfeeding diet, with one single male subject stuffing his face with 5,800 calories per day. (The average caloric intake for men is something like 2,800 to 3,500 or something.)

To underline: This is a study with just one participant, undergoing three different regimes.

Nina Teicholz, PhD @bigfatsurprise

Is weight all about calories-in vs. calories-out?

-->An overeating case study: A man ate 5800 calories/day for 3 weeks on 3 different diets.

Resulting weight gain:

Low-carb: 1.3 kg
Low-fat: 7.1 kg
V. low-fat vegan 4.7 kg

Obviously, not all calories produced the same results.

Subject felt best, had most energy on low-carb. Experienced no hunger on low-carb or vegan diets. Was hungry on the low-fat diet (!). Asthma, brain fog, sleep problems returned on low-fat and vegan diets. Excessive bathroom use was "unsettling" on vegan diet.

More info: Exercise was the same. 3-mo. washout period in between each diet to return to baseline

At pub time (2021), this was the only overfeeding experiment comparing low-carb to high-carb diets....

The study is here.

Leftwing freaks are proud of their culture and how they've changed society to valorize their degeneracy.

Here's are the victims of their culture war offensives: Almost one-in-three adolescents are now seeing shrinks for mental health issues.

In findings that suggest more young Americans struggling with mental health issues are getting the help they need, a new poll shows that nearly a third of American adolescents and teens received some sort of mental health treatment in 2023.

That translates to over 8 million young people between the ages of 12 and 17 getting counseling, medication or another treatment, the survey from the U.S. Substance Abuse and Mental Health Services Administration (SAMHSA) found.

"We're pleased to see that more people received mental health treatment in 2023 than the previous year," SAMHSA Adminstrator Miriam Delphin-Rittmon said in an agency news release announcing the survey.

You're pleased by this?

You're not even going to try to hide it, huh?

Money in your pocket! Nevermind how it gets there.

Among adolescents, the biggest increase from 2022 was in the number of those getting mental health medications: Nearly 14% of those age 12 to 17 received such a prescription in 2023, up from 12.8% the year before.

SAMHSA officials said they saw the increase shows that mental health treatment is finally being destigmatized.

It's not depression or alcohol or drug abuse that's driving these increases in childhood mental illness -- those stats are more or less flat.

So what is it?

Speaking of BRAINZZZ: There's new hope for treating Alzheimer's.

Scientists have identified a potential new target for treating Alzheimer's disease that works by restoring the brain's own "self-cleanup" process.

The target is already used in preexisting Parkinson's drugs and demonstrated partial reversal of cognitive deficits in aged study mice.

...

There is no known cure for Alzheimer's, although scientists believe that it is caused by the abnormal buildup of proteins in and around the brain cells. One of the major components of these abnormal aggregates is a protein called amyloid beta.

Amyloid beta is produced when proteins in the brain misfold and clump together. These clumps initiate a variety of damaging chemical reactions around our brain cells that damage and eventually destroy them.

Normally, our brain's cellular cleanup crew, which includes an enzyme called neprilysin, clears away any excess proteins and cellular debris.

"Neprilysin has been identified as the most potent amyloid beta degrading enzyme in the brain," Naoto Watamura, a research fellow at the UK Dementia Research Institute at University College London and the RIKEN Brain Sciences Center in Japan, told Newsweek.

However, preliminary evidence has shown that, as we age, levels of neprilysin in the brain tend to decline. Studies have also shown that genetically engineered mice that do not produce this enzyme develop very high levels of toxic amyloid beta protein clumps.

But while these findings suggest that neprilysin is a key player in the onset of neurodegenerative disease, methods to target and upregulate its activity have remained elusive--until now.

In a new study published in the journal Science Signaling, Watamura and colleagues from the RIKEN Brain Sciences Center screened a range of different candidate compounds and found one molecule that was able to upregulate the activity of this essential enzyme: dopamine.

"I was [surprised] because dopamine, which is likely to be the central role of Parkinson's disease, could have the potential to treat the aspect of Alzheimer's disease pathology," Watamura said.

Their findings may also offer insights into the established associations between dementia and mental health disorders related to low levels of dopamine.

Further research is needed to confirm these findings in humans, but the researchers are hopeful that their results may offer new targets for the treatment of Alzheimer's disease.

There's another new drug -- that just got blocked by the FDA for use in the US, but which is approved in 34 countries -- which supposedly is very helpful for sufferers of Parkinson's.

A little scienZZZ news for ya: A 500 million year old fossil of a larva has been discovered, with an intact brain.

Regime media immediately pronounced the 500 million year old fossil "sharp as a tack, probing, and in-command."

If you're not motivated to exercise, just tell yourself you'll do a couple of easy laps.

Old dog learns new poses.

The treadmill is scary at first but you get used to it.

Finishing up with a nice sprint.

Anyone want to brag on their GAINZZZ?

Or do you have RECOMENZZZ?

Or PROJEXXX? As you have no doubt heard on social media and legacy media, the Ac3 Sh3lving Phas3 Thr33 Initiativ3 starts today.

Or tomorrow. Whenever I get around to it, really.

(I just realized I have to go to Home Depot for screws and drywall anchors.)

posted by Disinformation Expert Ace at 04:20 PM

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