Ace of Spades HQ

« Cantor: We'll Be Including The Most Popular Basic Bits of ObamaCare When We Propose Our New Health Care Reform | Main | The Don't Ask, Don't Tell Report »

November 30, 2010

Uh-Oh: Age-Related Disease Reversed In Mice?

Hmmmm...

We wanted to know: If you could flip the telomerase switch on and restore telomeres in animals with entrenched age-related disease, what would happen? Would it slow down aging, stabilize it, or even reverse it? It was akin to a Ponce de León [the Spanish explorer looking for the Fountain of Youth] effect. When we flipped the telomerase switch on and looked a month later, the brains had largely returned to normal.
One of the most amazing changes was in the animals' testes, which were essentially barren as aging caused the death and elimination of sperm cells. When we restored telomerase, the testes produced new sperm cells, and the animals' fecundity was improved - their mates gave birth to larger litters.

Why the "uh-oh" in the headline? I don't know. Just seems so big, possibly, it deserves an uh-oh.

posted by Ace at 05:51 PM

| Access Comments


Advertise Here! Intermarkets' Privacy Policy Support Donate to Ace of Spades HQ! Contact Ace: aceofspadeshq at gee mail.com Buck: buck.throckmorton at protonmail.com CBD: cbd at cutjibnewsletter.com joe mannix: mannix2024 at proton.me MisHum: petmorons at gee mail.com J.J. Sefton: sefton at cutjibnewsletter.com Recent Entries Here Comes Johnny With His ONT In His Hand Fri-Yay Cafe The Weak Are Woke More: Graham Platner, Known to Have a Dick the Size of a Grain of Rice, Has Lied About Why He Has a Nazi Totenkopf on His Flabby Droopy Moob According To What Story He Thinks His Mark Wants to Hear Despite the Lies of the Biden Administration and Its Egregiously Dishonest Spokeswoman Jen Psaki, the US Did In Fact Use Taxpayer Money to Fund Bioweapon Labs Across the Globe, Including in Ukraine The Little Scottish Girl Smeared by the Left as a Racist Thug for Defending Her Sister Completely Vindicated as Bulgarian Brother and Sister Team Convicted of Assaulting and Making Sexual Remarks to a 12-Year-Old Child Democrat Lawmaker: If You Don't Give Us Reparations, We'll Stop Voting for Democrats Open Thread THE MORNING RANT Mid-Morning Art Thread Absent Friends Captain Whitebread 2026 Jon Ekdahl 2026 Jay Guevara 2025 Jim Sunk New Dawn 2025 Jewells45 2025 Bandersnatch 2024 GnuBreed 2024 Captain Hate 2023 moon_over_vermont 2023 westminsterdogshow 2023 Ann Wilson(Empire1) 2022 Dave In Texas 2022 Jesse in D.C. 2022 OregonMuse 2022 redc1c4 2021 Tami 2021 Chavez the Hugo 2020 Ibguy 2020 Rickl 2019 Joffen 2014 AoSHQ Writers Group A site for members of the Horde to post their stories seeking beta readers, editing help, brainstorming, and story ideas. Also to share links to potential publishing outlets, writing help sites, and videos posting tips to get published. Contact OrangeEnt for info: maildrop62 at proton dot me Cutting The Cord And Email Security Cutting The Cord [Joe Mannix (not a cop)] Cutting The Cord: It's Easier Than You Think [Blaster] Private Email and Secure Signatures [Hogmartin] Moron Meet-Ups NoVaMoMe 2026: 06/20/2026 Arlington VA Contact Bluebell/Weasel for info Texas MoMe 2026: 10/16/2026-10/17/2026 Corsicana,TX Contact Ben Had for info	« Cantor: We'll Be Including The Most Popular Basic Bits of ObamaCare When We Propose Our New Health Care Reform \| Main \| The Don't Ask, Don't Tell Report » November 30, 2010 Uh-Oh: Age-Related Disease Reversed In Mice? Hmmmm... We wanted to know: If you could flip the telomerase switch on and restore telomeres in animals with entrenched age-related disease, what would happen? Would it slow down aging, stabilize it, or even reverse it? It was akin to a Ponce de León [the Spanish explorer looking for the Fountain of Youth] effect. When we flipped the telomerase switch on and looked a month later, the brains had largely returned to normal. One of the most amazing changes was in the animals' testes, which were essentially barren as aging caused the death and elimination of sperm cells. When we restored telomerase, the testes produced new sperm cells, and the animals' fecundity was improved - their mates gave birth to larger litters. Why the "uh-oh" in the headline? I don't know. Just seems so big, possibly, it deserves an uh-oh. posted by Ace at 05:51 PM \| Access Comments <script language="javascript" src="http://adserver.adtechus.com/addyn/3.0/5235/1131537/0/170/ADTECH;loc=700;cookie=info;target=_blank;key=key1+key2+key3+key4;grp=[group]"></script><noscript><a href="http://adserver.adtechus.com/adlink/3.0/5235/1131537/0/170/ADTECH;loc=300;key=key1+key2+key3+key4;grp=[group]" target="_blank"><img src="http://adserver.adtechus.com/adserv/3.0/5235/1131537/0/170/ADTECH;loc=300;key=key1+key2+key3+key4;grp=[group]" border="0" width="300" height="250"></a></noscript>	Recent Comments garrett: ">>I love Idaho. But we were in Montana a couple we ..." Kindltot: "[i]That is the problem with dying in boredom. It i ..." mikeski: "[i]an owl can pick up a cat, skunk, possum...anybo ..." Mr Aspirin Factory: "Moose the Lab hunts groundhogs for sport. ..." Hour of the Wolf: "Once a dinosaur, always a dinosaur. Posted by: ..." Diogenes : "an owl can pick up a cat, skunk, possum...anybody ..." Archimedes: "At the Pittsburgh zoo, they have an Andean Condor, ..." Ace-Endorsed Author A.H. Lloyd: "His ambition may be to be god-emperor of Mars one ..." whig: "Hear Great Horned Owls here very often but I've ne ..." Pug Mahon, Born in Butte America: "I love Montana. Posted by: Wenda at June 12, 2026 ..." Braenyard - some Absent Friends are more equal than others _: "Crows flying over you going home to nest. It's li ..." Accomack: "Injury time is the stupidest thing in sports ..." Recent Entries Here Comes Johnny With His ONT In His Hand Fri-Yay Cafe The Weak Are Woke More: Graham Platner, Known to Have a Dick the Size of a Grain of Rice, Has Lied About Why He Has a Nazi Totenkopf on His Flabby Droopy Moob According To What Story He Thinks His Mark Wants to Hear Despite the Lies of the Biden Administration and Its Egregiously Dishonest Spokeswoman Jen Psaki, the US Did In Fact Use Taxpayer Money to Fund Bioweapon Labs Across the Globe, Including in Ukraine The Little Scottish Girl Smeared by the Left as a Racist Thug for Defending Her Sister Completely Vindicated as Bulgarian Brother and Sister Team Convicted of Assaulting and Making Sexual Remarks to a 12-Year-Old Child Democrat Lawmaker: If You Don't Give Us Reparations, We'll Stop Voting for Democrats Open Thread THE MORNING RANT Mid-Morning Art Thread Search Search this site: Polls! Polls! Polls! Frequently Asked Questions What is the Deal with the Cowbell? Why is the Ace of Spades called "the Death Card"? The (Almost) Complete Paul Anka Integrity Kick Primary Document: The Audio Paul Anka Haiku Contest Announcement Integrity SAT's: Entrance Exam for Paul Anka's Band AllahPundit's Paul Anka 45's Collection AnkaPundit: Paul Anka Takes Over the Site for a Weekend (Continues through to Monday's postings) George Bush Slices Don Rumsfeld Like an Fckin' Hammer Top Top Tens Democratic Forays into Erotica New Shows On Gore's DNC/MTV Network Nicknames for Potatoes, By People Who Really* Hate Potatoes Star Wars Euphemisms for Self-Abuse Signs You're at an Iraqi "Wedding Party" Signs Your Clown Has Gone Bad Signs That You, Geroge Michael, Should Probably Just Give It Up Signs of Hip-Hop Influence on John Kerry NYT Headlines Spinning Bush's Jobs Boom Things People Are More Likely to Say Than "Did You Hear What Al Franken Said Yesterday?" Signs that Paul Krugman Has Lost His Frickin' Mind All-Time Best NBA Players, According to Senator Robert Byrd Other Bad Things About the Jews, According to the Koran Signs That David Letterman Just Doesn't Care Anymore Examples of Bob Kerrey's Insufferable Racial Jackassery Signs Andy Rooney Is Going Senile Other Judgments Dick Clarke Made About Condi Rice Based on Her Appearance Collective Names for Groups of People John Kerry's Other Vietnam Super-Pets Cool Things About the XM8 Assault Rifle Media-Approved Facts About the Democrat Spy Changes to Make Christianity More "Inclusive" Secret John Kerry Senatorial Accomplishments John Edwards Campaign Excuses John Kerry Pick-Up Lines Changes Liberal Senator George Michell Will Make at Disney Torments in Dog-Hell Greatest Hitjobs The Ace of Spades HQ Sex-for-Money Skankathon A D&D Guide to the Democratic Candidates Margaret Cho: Just Not Funny More Margaret Cho Abuse Margaret Cho: Still Not Funny Iraqi Prisoner Claims He Was Raped... By Woman Wonkette Announces "Morning Zoo" Format John Kerry's "Plan" Causes Surrender of Moqtada al-Sadr's Militia World Muslim Leaders Apologize for Nick Berg's Beheading Michael Moore Goes on Lunchtime Manhattan Death-Spree Milestone: Oliver Willis Posts 400th "Fake News Article" Referencing Britney Spears Liberal Economists Rue a "New Decade of Greed" Artificial Insouciance: Maureen Dowd's Word Processor Revolts Against Her Numbing Imbecility Intelligence Officials Eye Blogs for Tips They Done Found Us Out, Cletus: Intrepid Internet Detective Figures Out Our Master Plan Shock: Josh Marshall Almost Mentions Sarin Discovery in Iraq Leather-Clad Biker Freaks Terrorize Australian Town When Clinton Was President, Torture Was Cool What Wonkette Means When She Explains What Tina Brown Means Wonkette's Stand-Up Act Wankette HQ Gay-Rumors Du Jour Here's What's Bugging Me: Goose and Slider My Own Micah Wright Style Confession of Dishonesty Outraged "Conservatives" React to the FMA An On-Line Impression of Dennis Miller Having Sex with a Kodiak Bear The Story the Rightwing Media Refuses to Report! Our Lunch with David "Glengarry Glen Ross" Mamet The House of Love: Paul Krugman A Michael Moore Mystery (TM) The Dowd-O-Matic! Liberal Consistency and Other Myths Kepler's Laws of Liberal Media Bias John Kerry-- The Splunge! Candidate "Divisive" Politics & "Attacks on Patriotism" (very long) The Donkey ("The Raven" parody) Syndicate this site (XML) Powered by Movable Type 2.64